from Lance McAlister's blog, The Lot D: 

Since 2000, the Reds have had 41 pitchers, who have been released, or otherwise parted company with the team...and who have not pitched in the major leagues again.

2000---Larry Luebbers, Keith Glauber
2001---Pete Harnisch, Osvaldo Fernandez, Lance Davis, Scott MacRae, Chris Piersoll, Justin Atchley, Frank Rodriguez
2002---Jose Rijo, Luis Pineda, Jose Silva
2003---Joey Hamilton, Jeff Austin, Josh Hall, Scott Randall, Phil Norton, Juan Cerros, Mark Watson
2004---Brian Reith, Jimmy Haynes, Todd Van Poppel, Jung Keun Bong, Jesus Sanchez, Aaron Myette
2005---Paul Wilson, Joe Valentine, Ben Weber
2006---Brandon Claussen, Brian Shackelford, Chris Michalak, Chris Hammond, Joe Mays, Esteban Yan, Jason Johnson, Sun-Woo Kim
2007---Eric Milton, Ricky Stone, Rheal Cormier, Elizardo Ramirez, Michael Gosling